Elder Rune of Protection and Sacrifice
Bane Effect:
The target must succeed on a Constitution saving throw or it can't regain hit points until a remove curse or greater restoration spell is cast on it.
Boon Effect:
The target is immune to the blinded, charmed, deafened, frightened, paralyzed, petrified, poisoned, and stunned conditions. In addition, the target stabilizes immediately when it drops to 0 hit points. This boon effect lasts for 24 hours.